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P., Duncans S

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Wu, Q., & Huang, F

While it is upregulated by Mn exposure (Yin et al., 2010), these studies used supraphysiological doses, and ferroportin likely functions primarily in Fe transport (Schulz et al., 2012

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The primary mechanism of action of camptothecin and its derivatives (trastuzumab, belotecan, irinotecan, topotecan) is through the binding to the DNA as well as topoisomerase II, which together make a ternary complex ( The naturally occurring flavonoid dihydromyricetin, derived from the plant Vitis heyneana traditionally used in Chinese herbal medicine, induced activation of p53 and apoptosis in ovarian cancer cells resistant to paclitaxel and doxorubicin ( Galangin, a flavonoid derived from the root of Alpinia galanga , has been shown to effectively inhibit multidrug-resistant cancer cells and exhibits collateral sensitivity, making it a promising therapeutic candidate ( Curcumin is a bioactive polyphenolic compound derived from the rhizomes of Curcuma longa