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The degree of synovial fibrosis was evaluated by calculating the positive area of collagen fibers and the percentage of collagen I positive areas with ImageJ (National Institutes of Health, USA, available at TUNEL staining The degree of apoptosis was detected by TUNEL staining in synovial tissues

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Mizutani T

Cadmium indirectly affects the generation of various radicals including superoxide and hydroxyl radical

These include genetics, environmental factors, and an overactive immune system
