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Rothuizen et al., 2020) and few months later a study on the association between routine use of NSAIDs and outcomes in hospitalized COVID-19 patients drawn completely different conclusions ( Indeed, a closer view to NSAIDs pharmacodynamics might lead to opposite conclusions on their therapeutic value in SARS-CoV-2 infection

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On the contrary, some studies denied the any beneficial effect of NAC administration through in vitro or in vivo model of experiments [35]

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[DOI] [PubMed] [Google Scholar] [110].Yamaguchi T, Sano K, Takakura K, Saito I, Shinohara Y, Asano T, Yasuhara H, Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial