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Regular water can promote bacterial growth which can degrade the peptide leading to loss of potency and contamination

RaissiDehkordi N., RaissiDehkordi N., Ebrahimibagha H., et al., Advancing Chronic and Acute Wound Healing With Cold Atmospheric Plasma: Cellular and Molecular Mechanisms, Benefits, Risks, and Future Directions, Frontiers in Medicine 12 (2025): 1527736

Results GSH synthesis is required for the survival of adult animals To better understand the importance of GSH in adult mammals, we developed an inducible, whole-body Gclc KO mouse by breeding the Gclc f/f mouse strain 30 with the Rosa26-CreERT2 mouse strain 31

However, the attempts to deplete GSH have been limited by the nonselective effects of BSO and have stimulated the research of new GCL inhibitors

Comparison of protrusion-derived and endosome-derived EVs Most EV engineering strategies for protein delivery have utilized endosome-derived EVs within the s-EV fraction 55,56

This was probably because DOXHCl diffused into the cells through passive diffusion without a release process and DOX-loaded micelles were internalized by the cells via a CD44 receptor-mediated endocytosis mechanism with a reduction-triggered release process, 62 which delayed the release of DOX in the first 4 h