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Five cellular phenotypes were identified: CD4 + helper T cells (CD45 + CD4 + CD3 + )

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The positive outcome may be attributed to the profound impact of ketones on multiple targets, including but not limited to glutamate/GABA transmission, monoamine levels, mitochondrial function and biogenesis, neurotrophism, oxidative stress, insulin dysfunction, and inflammation, and demonstrates mood-stabilizing and antidepressant effects (100)

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High-resolution analyses of GDAP1-deficient cells have revealed two distinct pathological mitochondrial phenotypes: (i) elongated, hyperfused mitochondria, and (ii) spheroidal, swollen organelles with disorganized cristae [12,13]

SARS-CoV-2 infection induces ferroptosis of sinoatrial node pacemaker cells