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First, the plasma membrane of the cell invaginates, forming a pocket around the target cargo [70]

Oxidative Medicine and Cellular Longevity, 2023, 121
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Biofilm could also reduce antibiotic penetration into bacterial cells, give them a slower metabolic rate, and easier exchange of resistance genes among cells [3]

doi: 10.1016/j.molbiopara.2008.09.005
