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However, the deleterious effects of anti-inflammatory medications in gastrointestinal, cardiovascular, hepatic, renal, cerebral, and pulmonary problems are alarmingly indicated by data from several placebo-controlled trials and meta-analyses of research [11]

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Choi SW, Friso S, Ghandour H, Bagley PJ, Selhub J, Mason JB: Vitamin B-12 deficiency induces anomalies of base substitution and methylation in the DNA of rat colonic epithelium

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