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doi: 10.1016/j.freeradbiomed.2013.08.002

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497502, www.ncbi.nlm.nih.gov/pmc/articles/PMC2596047/#:~:text=Glutathione%20plays%20a%20key%20role.

Wculek SK, Cueto FJ, Mujal AM, Melero I, Krummel MF, Sancho D
an isolated antibody is typically substantially free of other cellular material and/or chemicals

However, the contrasting nature of the results observed, particularly regarding the effects on cardiovascular morbidity and mortality in observational versus intervention studies, suggests that further research is warranted to support the repurposing of methotrexate for cardiovascular prevention (Table 1)
