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Since NDMA was already extensively investigated in various genotoxicity and mutagenicity assays and showed positive results in different in vitro comet assay studies, this substance was selected as the NA positive control for the present investigations

This eventually results in the dryness of hair follicles and accelerates hair loss

Testosterone, often associated with men, is an essential hormone for women as well

If macrophages are depleted with clodronate liposomes the blood-myenteric barrier remains intact, indicating that in a proinflammatory setting macrophage activation is deleterious to the integrity of the ENS