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The proteasome inhibitor bortezomib has improved treatment significantly, but inherent and acquired resistance to the drug remains a problem

Factors like poor nutrition, exposure to environmental toxins, chronic stress, and aging can impact glutathione levels in the body

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We explain five commonly used formulations.

Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

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