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A high clinical suspicion is needed when urine organic acids analysis is not available.

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As part of several multi-enzyme complexes located in the mitochondria, alpha-lipoic acid is essential for metabolizing carbohydrates, proteins, and fats, and for the conversion of their energy into ATP

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High levels of caffeine can also stress the adrenal glands, indirectly affecting the body's ability to maintain balanced glutathione levels

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