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To prevent later substrates from being phosphorylated by the early activated cyclin-Cdk complexes, these early complexes are typically characterized by lower intrinsic kinase activity

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In addition, there are variable number tandem repeats (VNTRs) in the MAOA gene that can affect MAOA levels

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Historical Background and Scientific Context Scientific interest in DSIP emerged during the twentieth century as researchers sought to better understand naturally occurring peptide messengers and their role in biological signalling systems

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15 , e1007671 (2019)

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