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A study based on the Global Burden of Disease showed that the global prevalence of substance use disorders was approximately 2.2%, with the prevalence of AUD (1.5%) being higher than other DUD (0.8%, including cannabis 0.32%, opioids 0.29%, amphetamines 0.10%, and cocaine 0.06%) (3)

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In 2024, Inchingolo et al reviewed 17 studies on the therapeutic effects of curcumin on oral health (Inchingolo et al., 2024)

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