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Crystallographic studies comparing the unliganded ECD of GHR to the ligand-bound form showed no major change in overall structure

10.1073/pnas.2322135121 38 GengJ.XuH.FuW.YuX.XuG.CaoH.et al (2020)

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In recent years, with advances in computational biology and medicinal chemistry, researchers have begun using computational simulation, virtual screening, and artificial intelligence techniques to identify anticancer candidates from natural products (258)

For example, sulfosuccinimidyl oleate (SSO), which irreversibly inhibits the fatty acid receptor CD36, has been shown to inhibit ferroptosis in CD8 + T cells by blocking the uptake of oxidized lipids

Our new work uncovering that glutathione (GSH) boosts tumor growth by supplying amino acids is now available at bioRxiv