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The PFC, essential for executive functions such as decisionmaking, working memory, and topdown emotional control, exhibits remodeling through experiencedependent changes in synaptic efficacy and spine density in layers II/III and V pyramidal neurons, particularly along the hippocampalPFC pathway [79, 80]

Deficiency of iPLA2 results in reduced docosahexaenoic acid (DHA) levels, elevated pro-inflammatory factors, and decreased levels of neuroprotective BDNF, thereby triggering microglial activation and inflammatory responses

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Workplace environments, particularly older office buildings, schools, or warehouses, may also pose risks if they have not been adequately maintained

Following Hhex deletion, Dax1 expression is increased in the male adrenal to levels comparable to the female adrenal, suggesting that HHEX is a crucial negative regulator of Dax1 expression

It is prescribed for the period of exacerbation of congenital, chronic diseases, frequent colds