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MOTS-c was found to upregulate key genes in the TGF-/Smad pathway (such as TGF-1, TGF-2, and Smad7) and increase the expression of bone formation markers like alkaline phosphatase (ALP), osteocalcin, and Runx2 in bone cells

So far, studies have not shown any genotoxic or carcinogenic effects associated with these peptides

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BPC-157 Therapy The action of peptide BPC-157 exhibits bacteriostatic effects, preventing the multiplication of pathogens

J Clin Oncol 20(21):43194323 Rajkumar SV et al (2010) Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial