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These studies help researchers better understand how tissues respond to stress and recovery conditions

Research in rat pinealocytes showed that epitalon upregulates two key enzymes in the melatonin synthesis pathway AANAT and pCREB directly stimulating endogenous melatonin production at the cellular level

Clinical studies need IRB oversight, and preclinical research must follow Animal Care and Use Committee (IACUC) guidelines, in accordance with the Animal Welfare Act (AWA)