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Ichijo H et al (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
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The present study provides evidence that increased OS within the aged ovary, elicits a concomitant increase in the electrophilic aldehyde by-product of 4-HNE, which appears to selectively accumulate within the oocyte
