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The physiologic stress response that occurs from mental or physical stress increases pro-inflammatory cytokines such as IL-2, IL-4, IL-6 and IL-10 which activates the HPA axis and increases production of epinephrine and cortisol and activates the TH-17 pathways that then promote autoimmunity

doi: 10.1007/s00401-006-0090-8

DHAR catalyses the reduction of DHA to AsA using glutathione (GSH) as a hydrogen donor before the spontaneous hydrolysis of DHA to irreversibly form 2,3-diketogulonic acid

Tesamorelin reduces visceral fat 1518%

doi: 10.1016/j.micpath.2021.105070

For best results, 23 sessions spaced 34 weeks apart are recommended