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Genetic variants related to the immune system and autoimmune diseases increases the risk of pernicious anemia

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One of the primary areas of investigation involves extracellular matrix remodeling and collagen regulation

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Caballero MR, Lukawska J, Lee TH, Dugu P

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Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)

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