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These studies vary widely in the oxidant properties examined, presence of added metals, cell type, and cellular context

Mechanisms and damaging effects of oxidative stress in COPD Oxidative stress is now recognised as a major predisposing factor in the pathogenesis of COPD and an excellent target for COPD therapies [37]

Also, the K112 and K198 residues are involved in prostaglandin H2 recognition (Kado et al., 2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] Huang P., Chen Y., Lin H., Yu L., Zhang L., Wang L., Zhu Y., Shi J

Xenobiotic transport and metabolism in the human brain