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CrAT deficiency leads to accumulating acetyl-CoA, which exerts an allosteric inhibiting effect on pyruvate dehydrogenase (PDH), a rate-limiting enzyme for pyruvate entry into the Krebs cycle

Antibodies against -actin (Sigma) were purchased from the indicated suppliers

(17) Lamb meat is comparable to bison meat in many ways

In inflammatory bowel disease (IBD) patients, significant reductions in Firmicutes and Proteobacteria have been noted, including a decrease in the Clostridium leptum group, particularly F

Additional findings are the development of purulent bile enriched in bile pigments and debris, bacterial infection, and intrahepatic stones in the right and left lobes, and extrahepatic ducts

Biochim Biophys Acta 1003, 270276