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Dose-finding studies for CNS effects in humans are needed because extrapolation from rat doses is unreliable
Myogenic differentiation induces taurine transporter in association with taurine-mediated cytoprotection in skeletal muscles
& Wu, S
And FDA regulators agreed, saying later that the substances "present significant safety risks," because most have not been extensively tested in humans
Tarozzi et al
Endothelin receptor A and p66Shc regulate spontaneous Ca2+ oscillations in smooth muscle cells controlling renal arterial spontaneous motion
