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In vitro , high iron level have been shown to directly stimulate the proliferation of human lung fibroblasts and enhance the secretion of ECM and pro-inflammatory factors (107)

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doi: 10.1016/j.neulet.2023.137346

Patients with HT who received replacement with levothyroxine (L-T4) did not always achieve clinically significant results, which requires additional therapeutic agents ( The significant prevalence of AITD, a long latent period and the involvement of autoimmune processes in their occurrence, development of concomitant diseases, insufficient effectiveness of the main pharmacotherapy, and a decrease in the quality of life of patients require the development of adequate approaches for the correction of immune processes in order to prevent and treat diseases

CrossRef Preliminary observation of thyroid function changes in subclinical thyroid diseases Hua-Xin Wang, Wen-Yu Gao, Yang Yang, Yun-Feng Li, Yan Zhang, Xin-Yi Zhang, Yu-Xia Li Technology and Health Care.2023

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