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A result is so-called hyperpolarization, which means the neuron is less likely to fire an electrical signal

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10.1002/art.34677 210 ZhangJ.ShuaiX.LiJ.XiangN.GongT.ZhangZ

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Development Beta Pharma, an American specialty pharmaceutical company, first synthesized icotinib in 2002.[1] Icotinib was subsequently developed, approved, and marketed in China through a joint venture with Chinese-based pharmaceutical company Betta Pharmaceuticals, Ltd