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Furthermore, in vitro experiments utilizing eight single-nucleotide polymorphisms in plasma revealed a GPX3 promoter H2 polymorphism, which was identified as a risk factor for arterial ischemic stroke and cerebral venous thrombosis in a limited cohort of young Brazilian adults

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This iron overload deposits in vital organs such as the heart, liver, and endocrine glands, leading to complications including cardiac dysfunction, liver disease, diabetes, and hormonal disturbances

[DOI] [PubMed] [Google Scholar] 15.Chang CW, Chen YS, Chou SH, Han CL, Chen YJ, Yang CC, Huang CY, Lo JF

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GSH, crucial for scavenging oxidants and preserving the redox-state balance in healthy cells, is strongly linked to GPx in the human body [109]