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In skin, the SIRTs are linked to the preservation of collagen in the dermis and their activation is important in wound healing and regeneration of skin by promoting keratinocyte proliferation

doi: 10.1016/S0891-5849(01)00640-2

(n = 3-6 independent experiments)

Maitane Prez Argeso 1 , Nagore del Molino Urquijo 1 , Sal Silvarrey Rodrguez 1 , Begoa Huete Antn 1 , Juan Manuel Garcia Sanchez 1 , Borja Aguilera Irazabal 1 , Naroa Arenaza Basterrechea 1 , Juan Carlos Garca-Monco Carra 1 1 Hospital Universitario de Basurto, Bilbao, Spain Background and Aims: Mechanical thrombectomy (MT) has demonstrated significant benefits in patients meeting strict ESOC guidelines criteria: mRS1, large vessel occlusion (internal carotid artery, M1 segment of the middle cerebral artery or basilar artery), NIHSS6, ASPECTS6 and a door-to-needle time 6 hours or 24 hours with a favourable mismatch on multimodal CT

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