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Jannin A, Escande A, Al Ghuzlan A, et al

Two-dimensional electrophoresis combines isoelectric focusing (first dimension, by pI) with SDS-PAGE (second dimension, by molecular weight), resolving thousands of proteins from a cell lysate into a characteristic spot pattern

This is relevant since treatment goals may differ between HCPs and patients

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Treatment with Wy 14,643 similarly reversed the downregulation of CPT1A and ACADM in NaOX-treated cells (Extended Data Fig