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Furthermore, aminoglycoside antibiotics may also have toxic effects on the auditory nerve itself, interfering with its conduction function and exacerbating hearing problems

Through the application of this methodology across various mutants, we identified that glr3.3glr3.6 , msl10-1 , and mca1mca2 mutants exhibited a delayed peak in local Ca 2+ elevation

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In addition, ROS are also formed by the arsenic-mediated stimulation of an electron-transporting membrane-located enzyme complex, NADPH oxidases (NOXs), or arsenic-induced release of the free iron pool from the iron-storage protein ferritin (Shi et al

The lysate was clarified through a series of 60 m Clarisolve 60HX (Cat#: CS60HX01L3, MilliporeSigma) and 1.2 m Sartopure GF+ (Cat#: 5555303 PV, Sartorius AG) filters to remove microcarriers and large cell debris to generate the clarified bulk (CB)