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Vitamin B12 deficiency can be occurring while vitamin B12 levels are at levels not typically associated with deficiency due to the presence of deleterious MTHFR mutations. 5 If you have one or more MTHFR, MTRR or MTR gene mutations, you will be less able to methylate B12 or convert your B12 to methylcobalamin

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[DOI] [PubMed] [Google Scholar] 89.Schwartz JC, Arrang JM, Garbarg M, Pollard H, Ruat M

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Titrate: Increase by roughly 100 mcg every 24 weeks as tolerated

Vitamin B12 is a water-soluble vitamin that plays a crucial role in several bodily functions