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You know the culprits: estrogen and testosterone, primarily
Sesso HD, Buring JE, Christen WG, Kurth T, Belanger C, MacFadyen J, Bubes V, Manson JE, Glynn RJ, Gaziano JM, Vitamins E
where they can unfold their effect
Fournier, A., Berrino, F., & Clavel-Chapelon, F
127 Invasion and metastasis The invasion-metastasis cascade is the defining phenotype of tumor cell proliferation and is recognized as the most lethal aspect of tumor progression
doi: 10.1371/journal.pone.0166291
