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FIGURE 2 Cytotoxicity of AQ-QI and DEAQ-QI was time-dependent during the first 3 h of exposure (Supplementary Figure S3)

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This rescue of acetyl-CoA labeling was accompanied by a rescue of labeling in the downstream TCA cycle metabolites citrate and succinate

These findings have important implications for developing therapeutic strategies through regulate apoptosis of keratinocytes in psoriasis, and Prx II inhibitors may be exploited as a therapeutic drug to alleviate psoriatic symptoms

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without such validation, false-positive results may occur (Shi et al., 2024)