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A recent randomized controlled trial assessing 1 mg daily oral folic acid supplementation found no significant changes in liver enzymes, lipid profiles, insulin resistance, or hepatic steatosis grade [190]

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Some owners notice small shifts in a few weeksslightly better play tolerance or easier portion controlwhile body condition and coat presentation usually take longer because they reflect consistent routine

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Correspondingly, this extremely thin layer of film is constituted by an even thinner top layer of lipid (about 42 nm) [10] and a mucin-aqueous (mucoaqueous) layer with decreasing concentration of mucins from the cornea epithelium towards the lipid layer [11, 12]