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Irreversibility of pulmonary fibrosis

Wogonoside can significantly reduce airway inflammation and excessive mucus production while enhancing airway remodeling by inhibiting the activation of NF-B and STAT6 in lung tissue and bronchial epithelial cells, as well as decreasing Th2-related cytokines (IL-4, IL-5, IL-13) in lung tissue and serum IgE levels (315)

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Ishibashi M, Akazawa S, Sakamaki H, Matsumoto K, Yamasaki H, Yamaguchi Y, Goto S, Urata Y, Kondo T, Nagataki S: Oxygen-induced embryopathy and the significance of glutathione-dependent antioxidant system in the rat embryo during early organogenesis

in vitro , BPC-157 (VEGF) (FGF)