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In a comprehensive US administrative database from 2005 to 2008, GLP-1-based treatments, particularly sitagliptin and exenatide, were associated with a significantly increased risk of acute pancreatitis-related hospitalization in adults with T2DM [59], thereby reinforcing prior mechanistic experimental studies and spontaneous reports to the FDA suggesting a potential causal relationship

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According to a study on the structure-activity relationship, having a two-carbon chain in the taurine molecule is vital for better action of these derivatives

doi: 10.1016/j.exer.2017.06.018

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10.3934/NEUROSCIENCE.2023017 135 RayS.SinghN.KumarR.PatelK.PandeyS.DattaD.et al (2020)