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It is worth mentioning that ebselen does not contribute to the bioavailable selenium pool required for the biosynthesis of selenoproteins including seleno-GPxs and therefore its ability to detoxify hydroperoxides under cellular conditions can exclusively be attributed to GPx mimicking activity [77, 79]

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Global prevalence of post-coronavirus disease 2019 (COVID-19) condition or long COVID: a meta-analysis and systematic review

Many other studies provide evidence that a deficiency of GPx1 can exacerbate cardiac dysfunction