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Description
& Gray, D
We would like to acknowledge the microscopy support from the Infectious Diseases Imaging Platform (IDIP) at the Center for Integrative Infectious Disease Research, Heidelberg, Germany

coli in vitro and in vivo

Gallstone disease and microbiome

By converting lipid peroxides (L-OOH) into non-toxic lipids, GPX4 counteracts oxygen- and iron-dependent lipid peroxidation, with GSH acting as a crucial cofactor

under ferroptotic conditions, lysosomal leakage releases hydrolytic enzymes and iron-rich contents into the cytosol, amplifying oxidative stress (72)
