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Mitochondria also play other roles in synaptic regulation including calcium buffering, the regulation of neurotransmitter release, and reduction in oxidative stress [11]

Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice

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In clinical studies, a 5-HT 1A partial agonist, buspirone, has potential effects on various symptoms of ASD, particularly anxiety [36, 37]

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It's believed to be a very safe compound to use even at extremely high levels - and the scientists are hypothesizing that it might have significant value at much lower doses to maintain glutathione levels and improve health