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Furthermore, natural compounds such as resveratrol activate SIRT1, suppressing p53-mediated apoptosis and enhancing antioxidant defenses (Li et al., 2021)
Specifically, in 2020, an open-label phase 1/2 clinical trial was planned to evaluate the safety and efficacy of four intravenous infusions of Hope Biosciences adipose-derived mesenchymal stem cells (HB-adMSCs) [59]
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