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[DOI] [PubMed] [Google Scholar] 40.Fang JH, Lai YH, Chiu TL, Chen YY, Hu SH, Chen SY

PARP inhibition + metabolic stress: PARP inhibitors trap PARP proteins on DNA, creating DNA damage that requires homologous recombination for repair

HO-1 was involved in the protective effect of telmisartan against DN, and the mRNA levels regulation of Nrf2 and HO-1 indicated that telmisartan had a regulatory effect on apoptosis besides anti-inflammation and anti-oxidation [153]

In the following sections, we will use this framework to examine emerging evidence of the impact of G6PD-d on three major ASCVD-mediating immune cells: macrophages, T cells and B cells
Liu Z., Ran Y., Huang S., et al., Curcumin Protects Against Ischemic Stroke by Titrating Microglia/Macrophage Polarization, Frontiers in Aging Neuroscience 9 (2017): 233

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