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Learn where to self-administer a B12 shot and how to do it painlessly This article was medically reviewed by Shari Forschen, NP, MA and by wikiHow staff writer, Amber Crain

B12 injections are ideal for those who: Have a diagnosed B12 deficiency Dont absorb B12 well from food or supplements Need fast symptom relief If you are following a vegan or vegetarian diet (since B12 is found mostly in animal products) Your provider may recommend blood testing to confirm a deficiency and tailor a dosing schedule that fits your goals

Like sterile water, saline doesn't contain bacteriostatic preservatives

Aids in Treatment for Depression Many factors can lead to you getting diagnosed with depression, and some patients may have to be on long-term medication to battle depression

Though the link isnt well understood, scientists have linked the vitamin to serotonin and depression in people with a deficiency

TNF , whose baseline mRNA levels were low only in the SEV group compared to CTRL at endpoint A, did not have their mRNA levels significantly altered by B12 in either of the two patient groups