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There is a significant difference for the secondary outcome, FSH level in one group, which favored combination with LC (MD0.50, 95% CI [0.84 to 0.16]

13 Complicating this further, excessive insulin levelsanother prominent feature of a high percentage of cases of PCOSalso contribute to hyperandrogenism

PMID: 35499819

Third, all included studies were conducted prior to 2006

For example, high glucose promotes inflammation as well as glycation, and perturbs blood flow to neurons, all of which contribute to neuropathy

498,499 Smoking is an independent risk factor for DN and microvascular complications
