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2 The SNPs would be specifically removed for the analysis in Figure 1A if related to hypertension, diabetes, smoking, obesity, depression, cholesterol, and hard of hearing on AD (26), head trauma, intake of antioxidants, and smoking on ALS (27, 28), caffeine consumption on PD (29)

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Abstract Background Transthyretin (TTR) amyloidosis is a progressive, life-threatening disorder caused by extracellular deposition of amyloid fibrils derived from the plasma protein TTR

Posttranslational Modifications and Protein Interactions of Glial Fibrillary Acidic Protein and Their Alterations in Alexander Disease Detection of high molecular weight forms of GFAP AxD mutants, resistant under various denaturing conditions, suggests the occurrence of various posttranslational modifications, potentially including crosslinks (Viedma-Poyatos et al., 2022