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Neurotoxic metals such as lead, mercury, aluminum, cadmium and arsenic, as well as some pesticides and metal-based nanoparticles have been involved in AD due to their ability to increase beta-amyloid (A) peptide and the phosphorylation of Tau protein (P-Tau), causing senile/amyloid plaques and neurofibrillary tangles (NFTs) characteristic of AD

Curr Issues Mol Biol 45:45744588 [DOI] [PMC free article] [PubMed] [Google Scholar] 182.Comini G, Kelly R, Jarrin S, Patton T, Narasimhan K, Pandit A, Drummond N, Kunath T, Dowd E (2024) Survival and maturation of human induced pluripotent stem cell-derived dopaminergic progenitors in the parkinsonian rat brain is enhanced by transplantation in a neurotrophin-enriched hydrogel

Effects of Melatonin and/or Magnesium Supplementation on Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial

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Parsonage G, Filer A, Bik M, Hardie D, Lax S, Howlett K, et al

J Neuroimmunol (2014), 273(12)2230