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[14] Through comparison to the structural data of the homologous enzyme xylanase, it has been suggested that Tyr504 of -glucuronidase might stabilize the leaving nucleophile (Glu540) or modulate its activity

[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Bourgeron T

First, it acts as a glutathione-sparing agent by immediately attacking free radicals

Proc Natl Acad Sci U S A 108: 7601-7606, 2011

Levenson JM, Schroeter S, Carroll JC, Cullen V, Asp E, Proschitsky M, Chung CH-Y, Gilead S, Nadeem M, Dodiya HB et al (2016) NPT088 reduces both amyloid- and tau pathologies in transgenic mice

Psychiatry 2 , e134 (2012)