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Chemistry [edit] In the kidneys, the enzyme AGAT catalyzes the conversion of two amino acidsarginine and glycineinto guanidinoacetate (also called glycocyamine or GAA), which is then transported in the blood to the liver

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[DOI] [PubMed] [Google Scholar] 124.El-Sayed SS, Shahin RM, Fahmy A, Elshazly SM

Therefore, therapeutic strategies must carefully balance targeting AMPK in MDSCs while minimizing potential harm to non-cancerous cells
