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PMID 32365821

Dioscorea opposita is neutral in nature, strengthening the spleen and kidneys, and can help improve indigestion, diabetes, and chronic kidney disease

Rinsho Byori 52(8):642-648, 2004

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The mechanisms underlying these effects may involve protection of pancreatic beta-cells from oxidative damage 4 , repression of hepatic gluconeogenesis and lipid synthesis 5 , and regulation of muscle glycogen metabolism 6

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