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In sorafenib-treated hepatocellular carcinoma (HCC) cells, autophagy was activated to inhibit apoptosis and mediate cellular chemoresistance [136], but sorafenib also induced autophagy-dependent ferroptosis in HCC cells [130]

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Weight reduction in obese subjects causes a substantial increase and normalization of sensitivity to catecholamine stimulation of lipolysis (77) without changing the number of -adrenergic receptors (102)

Cell Death Differ, 2006

[DOI] [PMC free article] [PubMed] [Google Scholar] Verma NK, and Kelleher D (2017)

It may contain little, or no active ingredient, or higher than the needed amount of active ingredient, which may affect the effectiveness of the medication