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Pathol., 86: 591-600

Forms of B12 supplements available include: Cyanocobalamin : The most common and cost-effective form in over-the-counter supplements Methylcobalamin : A naturally occurring form, often marketed as superior though evidence for clinical advantage is limited Hydroxocobalamin : The preferred form for intramuscular injection in the UK, used therapeutically for pernicious anaemia and confirmed deficiency [4] Dosing considerations depend on the indication

Practical tips for taking it To get the best possible effect from your oral B12 supplement, follow these recommendations: Take on an empty stomach: For best absorption, you should take your B12 supplement in the morning before breakfast or between meals with a glass of water

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Pure Encapsulations B12 comes in a convenient liquid form that can be administered sublingually for optimal absorption