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In support of this idea, knockdown of Caenorhabditis elegans gst-10 that encodes a detoxifying enzyme with high catalytic activity toward 4-HNE, reduced lifespan 13 , while overexpression of gst-10 or murine Gsta4 increased lifespan 14

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[DOI] [PubMed] [Google Scholar] 173.Bilic Z., Gojkovic S., Kalogjera L., Krezic I., Malekinusic D., Knezevic M., Sever M., Lojo N., Kokot A., Kasnik K., et al

LRS itself is able to detect 3% more CpGs than the short-read sequencing methods, due to its ability to accurately capture challenging regions